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It looks like you are asking for a description of major developments and key personalities in Science and Technology (S&T) in the Philippines. Below is a detailed overview:

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### **Major Developments in Science & Technology in the Philippines**

1. **Pre-Colonial and Colonial Period**
- Indigenous Filipinos developed agricultural techniques, boat-building, and herbal medicine.
- During the Spanish era, scientific institutions like the Manila Observatory (1865) were established.

2. **American Period (1898-1946)**
- The U.S. introduced modern education and research institutions, including the Bureau of Science (1901).
- The University of the Philippines (UP) was founded in 1908, promoting higher education in S&T.

3. **Post-War and Industrialization Period (1946-1970s)**
- The Science Act of 1958 led to the creation of the National Science Development Board (NSDB), now known as DOST.
- Government initiatives expanded research in agriculture, health, and engineering.

4. **Martial Law and Science Growth (1970s-1980s)**
- The Marcos administration established the Philippine Council for Agricultural Research and the Philippine Science High School.
- Technology development focused on self-sufficiency in food production.

5. **Modern Era (1990s-Present)**
- The Department of Science and Technology (DOST) expanded research in biotechnology, space science, and disaster preparedness.
- Notable projects include the **Diwata-1 and Diwata-2 satellites**, and the **Balik Scientist Program** for returning Filipino scientists.

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### **Key Personalities in Philippine S&T**

1. **Dr. Fe del Mundo** – The first woman admitted to Harvard Medical School, known for her work in pediatrics and rural medicine.
2. **Dr. Angel Alcala** – A marine biologist known for establishing marine protected areas and advancing biodiversity conservation.
3. **Dr. Gregorio Zara** – A physicist and engineer who invented the two-way videophone.
4. **Dr. William Padolina** – Former DOST Secretary who helped develop agricultural biotechnology.
5. **Dr. Lourdes Cruz** – A biochemist recognized for her research on marine toxins from cone snails, useful in medical applications.
6. **Dr. Enrique Ostrea** – Invented meconium drug testing for detecting drug exposure in newborns.
7. **Dr. Rafael Guerrero III** – Developed the sex reversal technology for tilapia farming.
8. **Dr. Edgardo Gomez** – Led efforts in coral reef conservation in the Philippines.

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### **Conclusion**
The Philippines has made significant progress in S&T, focusing on health, agriculture, environmental conservation, and space technology. Filipino scientists continue to contribute globally, ensuring innovation and development in the country.